Invariant Natural Killer T Cells: Boon or Bane in Immunity to Intracellular Bacterial Infections?

Calotropis boon or bane?

The herbal medicine occupy distinct position right from ancient period. The plant Calotorpis procera is known by different name in different part of world like French cotton, Alarka, or Madar, Rooster tree, and Widuri. The plant is poisonous can lead to blindness if its juice is put in to the eyes. The same plant is used for Ayurvedic medicines. The medicinal properties like Calotropin isolated...

Invariant Natural Killer T Cells

Invariant Natural killer T cell (iNKT cells) are a subset of T cells, which are narrowly defined as a T cell lineage expressing a semi-invariant CD1d-restricted T cell Receptors (TCRs) composed by Vα24-Jα18/Vβ11 in human, and Vα14-Jα18/Vβ8,Vβ7, and Vβ2 in mouse. Unlike conventional T cells which recognize peptides bound to highly polymorphic major histocompatibility complex (MHC) class I and II...

Tax Competition : Bane or Boon ?

Comparison of Two Flow Cytometric Methods for Detection of Human Invariant Natural Killer T Cells (iNKT)

Background: Invariant natural killer cells (iNKT) are an important immunoregulatory T cell subset. Currently several flow cytometry-based approaches exist for the identifi-cation of iNKT cells, which rely on using the 6B11 monoclonal antibody or a combina-tion of anti-Vα24 and anti-Vβ11 antibodies. Objective: The aim of this study was to compare the ability of two flow cytometry-based methods f...

Fog in GATS commitments : Boon or bane ?

The creation of the General Agreement on Trade in Services (GATS), in the Uruguay Round, and its entry into force in 1995 marked a new stage in the history of the multilateral system. It was motivated essentially by the rapid expansion of international services trade within an increasingly open environment in many countries. Given the peculiarities of services trade, including the intangible na...